Patrick Lyden, MD, FANA
Keck School of Medicine of USC
Patrick Lyden, MD, FANA, is professor of physiology & neuroscience and neurology at the Zilkha Neurogenetic Institute in the Keck School of Medicine at USC. He is recognized globally for leadership in stroke therapy, having led large, multi-national trials for NIH and industry. Dr. Lyden helped lead the pivotal trial of Tissue Plasminogen Activator (TPA), the first proven therapy for stroke. Dr. Lyden is the principal investigator of the NIH-sponsored Stroke Preclinical Assessment Network (SPAN). He is the past chair of the Stroke Council of the American Heart Association/American Stroke Association. In 2019, he was awarded the prestigious William M. Feinberg Award for Excellence in Clinical Stroke by the American Heart Association. In 2023, he received the Neurology Pioneer Award from the Society for Vascular and Interventional Neurology. Dr. Lyden’s laboratory works on finding new treatments for stroke and understanding how the brain acts to save itself during stroke. Recently, the Lyden Lab discovered a novel ‘help-me’ signal internal to the brain, and internal responses that mean the brain is trying to protect itself. Now the lab seeks to translate this finding into novel treatment for stroke.