Cognitive Decline in Older Adults
Description
In this presentation, Dr. Sarkis will discuss cognitive decline in older adults with epilepsy, including the risk of dementia and the role of neurodegenerative biomarkers.
Epilepsy and the Aging Brain*
Date: October 19, 2026
Time: 3:45 pm to 5:15 pm
Room: Coral 3
Track: Traditional Special Interest Group (SIG)
Session Description
This session will examine the unique features of epilepsy in older adults, with a focus on new-onset unprovoked seizures (late-onset epilepsy) and the evaluation and management of cognitive impairment in patients with longstanding epilepsy. Faculty will discuss the relationship between epilepsy and Alzheimer’s disease, including the role of biomarker testing, neuropsychological assessment, and potential implications for emerging therapies. Case-based discussions and debates will highlight practical approaches to diagnosis, prognosis, and management in this population.
Learning Objectives
At the conclusion of this session, attendees will be able to:
- Describe current evidence on the prevalence of Alzheimer’s pathology in late-onset epilepsy.
- Assess the prognostic value of Alzheimer’s biomarker testing in this population.
- Identify clinical scenarios in which neuropsychological assessment or Alzheimer’s biomarker testing may be appropriate.
Speakers
- (Chair) James Gugger, MD, PharmD
- (Co-Chair) Heidi Munger Clary, MD, MPH, FACNS, FAES, FANA
- (Speaker) Rani Sarkis, MD, MSc
- (Speaker) Keith Vossel, MD, MSc
- (Panelist) Ifrah Zawar, MD, MS-CR
Debate Session
Description
In this presentation, Dr. Vossel will discuss the unique aspects of epilepsy in the elderly with a focus on new onset of unprovoked seizures in the elderly.